Funding Breakthrough Research to Cure ALD

We Can Will Cure ALD

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Exciting things are in motion:

Read our December 2025 donor update and progress report here

We started Will to Cure ALD after our son William was diagnosed at birth with X-Linked Adrenoleukodystrophy (ALD), a rare genetic disease with no cure. After realizing what this meant for our family, we began looking into the research landscape for ALD and it became clear that funding was limited and fragmented, so we decided to help change that. Since late 2024, we have raised over $2.5 million and have issued grants across all six major ALD research institutions. We are backing a diversified portfolio of projects aimed at advancing new treatment options, and we intend to keep building on this foundation. Our vision is simple: within the next 5–10 years, families facing ALD should have more and better treatment options. We believe thoughtful, coordinated funding can make that achievable.

Our Story

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Funding Impact

We thoughtfully fund a diversified portfolio of translational research projects across all major ALD institutions. We believe each of these institutions brings individual strengths and perspectives to the table. Our goal is to accelerate multiple treatment pathways while also fostering collaboration.

Explore our Funding Impact

Fundraising Progress

We have an angel donor that will match contributions for the next $250,000 in donations, so every dollar donated has double the impact

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Our Supported Organizations

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Our Focus Areas

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Pillar #1: New Treatments for Cerebral ALD

Despite ALD affecting 1-in-17,000 individuals worldwide, treatment options are limited and there is no cure. We aim to fund research to develop breakthrough treatments for pediatric and adult patients with Cerebral ALD. Until recent gene therapy discoveries, a bone marrow transplant was the only available treatment for Cerebral ALD.

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Pillar #2: New Treatments for AMN

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AMN (Adrenomyeloneuropathy) occurs when ALD manifests in the spinal cord leading to mobility challenges. This form of ALD affects both men and women. We aim to support research focused on developing new treatments for this form of ALD, which currently has no cure.

Pillar #3: Prognosis and Outcome Prediction

There is currently no way to predict how ALD will manifest (if at all). Our goal is to fund research that uses biomarkers and data science to predict outcomes. This will support efforts to develop cures and take timely action to prevent severe outcomes.